The Anti-Ms CD106 FITC Antibody from MyBioSource.com is a Rat Monoclonal antibody to VCAM1. This antibody recognizes Mouse antigen. The Anti-Ms CD106 FITC Antibody has been validated for the following applications: Flow Cytometry.
Description
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity